Publications + Posters

LIG1 inactivation selectively inhibits growth of BRCA1 mutant cells in vitro and in vivo

Hilary Nicholson, et al.

Stearoyl-CoA desaturase is a synthetic lethal target in SMAD4-deficient cancers

Alvin Lu, et al.

| Applied Pharmaceutical Chemistry

MTA-cooperative PRMT5 inhibitors for the treatment of MTAP-deleted cancers

Kevin M. Cottrell, et al.

| ACS National Meeting

Discovery of TNG348: A selective and potent inhibitor of USP1 for treatment of BRCA1, BRCA2-mutant and other HRD+ cancers

| GRC DNA Damage, Mutation and Cancer

POLB knockout is synthetic lethal with PARP inhibition leading to complete and durable responses in BRCA-mutant tumor xenografts

Madhavi Bandi, et al.

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