Publications + Posters

Hit finding and assay enablement for MGAT1, a novel glycosyltransferase involved in cancer cell immune evasion

APEX2 is a synthetic lethal target for RNASEH2B-deleted or BRCA-mutant tumors

TNG961: A selective oral molecular glue degrader of HBS1L inducing tumor regression in naïve and PRMT5i-refractory FOCAD-deleted models

TNG260 is a Small-Molecule CoREST Inhibitor that Sensitizes STK11-Mutant Tumors to Anti-PD-1 Immunotherapy

MTA-Cooperative PRMT5 Inhibitors are Efficacious in MTAP-Deleted Malignant Peripheral Nerve Sheath Tumor Models